ABOUT · TWO:4168 · TAIPEI

Founded in 2001. Listed on the Taipei OTC. Built around glycobiology.

GlycoNex develops antibody-drug conjugates, pro-antibodies, and biosimilars, from its Taipei facility.

Founded
2001
in Taipei
Listing
TWO:4168
OTC since 2012
Pipeline
6 programs
in clinical and preclinical development
Manufacturing
50 + 200 L
in-house GMP capacity
Patents
36 granted
01 — Who we are

A clinical-stage biotech rooted in two decades of glycobiology

GlycoNex, Inc. (TWO:4168) was founded in 2001 from a technology licensing agreement with Kyowa Hakko Kirin (KHK) and an academic collaboration with The Biomembrane Institute (TBI). Dr. Sen-itiroh Hakomori — academic co-founder of GlycoNex, professor at the University of Washington, and a foundational figure in tumor-associated carbohydrate antigen (TACA) research — led the glycobiology work that anchors GlycoNex's scientific approach. Over the following two decades, GlycoNex assembled a proprietary anti-glycan antibody library (the GlycoSH platform), advanced clinical and preclinical pipelines across three modalities, and built a GMP-compliant antibody manufacturing facility in Xizhi, New Taipei City.

The company operates today as a vertically integrated organization — from antibody discovery and process development through GMP production and clinical operations. Revenue is generated through asset out-licensing, technology services, and CDMO partnerships, alongside sustained research investment.

Innovative Drug

Anti-glycan antibodies against tumor-associated carbohydrate antigens — sourced from the GlycoSH antibody bank — anchor a pipeline of antibody-drug conjugates, pro-antibody ADCs, and bispecific ADCs. Lead candidate GNX1021 entered Phase 1 in 2026; GNX201-ADC and GNX203 are in preclinical development.

View pipeline →

Service (CDMO)

200 L GMP antibody manufacturing supports both internal pipeline and external partners. Current and historical clients include Change Cure (HMGB1-targeted antibody, 2025), with manufacturing collaborations with Sterling Pharma Solutions and EirGenix.

CDMO services →

Biosimilar

Two programs in development. SPD8 (denosumab biosimilar, Phase 3 complete) is co-developed with Mitsubishi Gas Chemical of Japan; SSR (a biosimilar for an autoimmune disease) is developed in-house.

View pipeline →
02 — Leadership

The people behind GlycoNex

Dr. Tong-Hsuan Chang
Dr. Tong-Hsuan Chang
Founder & Chairman

Dr. Tong-Hsuan Chang, founder and Chairman of GlycoNex, holds a PhD in Pharmaceutical Sciences from the University of Tokyo. After research stints in the United States covering allergy, hormone receptors, monoclonal antibodies, and tumor markers, he led Syncor Biomedical Group before returning to Taiwan. He has served as Visiting Professor at National Taiwan University and as Director (and acting CEO) of the Immunology Division at Taiwan's Development Center for Biotechnology (DCB). His career has been instrumental in shaping Taiwan's monoclonal antibody and diagnostic reagent industry.

Dr. Mei-Chun Yang
Dr. Mei-Chun Yang
President & CEO

Dr. Mei-Chun Yang, President and CEO of GlycoNex, holds a PhD in Pharmaceutical Sciences from Taipei Medical University. Prior to joining GlycoNex, she served as Associate Researcher at Taiwan's Development Center for Biotechnology (DCB) and as R&D Manager at TaiGen Biotechnology. She joined GlycoNex as Vice President before being promoted to her current role, where she leads the company's clinical translation, partnership strategy, and asset commercialization efforts.

Management Team

GlycoNex's day-to-day operations are led by a management team spanning research and development, clinical development, manufacturing, quality, and corporate functions.

Roger Lu
Roger Lu
Vice President of Administration
Liang-Yrin Liu
Liang-Yrin Liu
Vice President of R&D
Ti-Fen Wu
Ti-Fen Wu
Chief Financial Officer
Yen-Ying Chen
Yen-Ying Chen, Ph.D.
Head of New Drug Development
Yu-Ting Lin
Yu-Ting Lin
Head of Clinical Development
Chun-Fu Lin
Chun-Fu Lin
Head of Manufacturing
Jong-Jing Wang
Jong-Jing Wang
Head of Quality Assurance
Tzu-Lin Yang
Tzu-Lin Yang
Head of Process Development
Chieh-Hsin Chen
Chieh-Hsin Chen
Head of Analytical Development & QC
Wen-Han Lee
Wen-Han Lee, Ph.D.
Head of Strategy & Business Development
Scientific & Development Advisors

Beyond its executive leadership, GlycoNex draws on an international advisory board spanning the full drug development chain — from preclinical research and CMC development through clinical trial design and business development.

Josette Carnahan
Josette Carnahan, Ph.D.
CEO, Josette Carnahan Consulting, LLC · Preclinical Development Advisor
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Specialist in monoclonal antibody development and preclinical biopharmaceutical strategy. Long tenure at Amgen contributing to oncology and neuroscience drug discovery, including co-authorship on the foundational in vitro characterization of epratuzumab — a humanized anti-CD22 IgG1 monoclonal antibody (Clin Cancer Res, 2003). Founder and CEO of Josette Carnahan Consulting, LLC. Ph.D. in Molecular and Cellular Biology (developmental neuroscience), Université Louis Pasteur, Strasbourg.

Hiromi Ishii
Hiromi Ishii
Independent Drug Development Consultant (since 2016) · Preclinical Development Advisor
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Over three decades in Japanese pharmaceutical non-clinical development, spanning toxicology, regulatory affairs, and CTD/eCTD submission. Previously General Manager of Non-Clinical Development at Fujifilm Kyowa Kirin Biologics, leading non-clinical programs for biosimilar antibody products, and earlier a Non-Clinical Development manager at Kyowa-Hakko Kirin. Began his career at Kirin Brewery's pharmaceutical division as a toxicology study director and chief pathologist. Since 2016, an independent consultant across small-molecule, antibody (including biosimilars), nucleic-acid, and cell-and-gene-therapy modalities. Licensed veterinarian (DVM, 1987); M.S. in pathology, Nippon Veterinary and Zootechnical College.

Kent Iverson
Kent Iverson
Independent CMC Consultant (since 2001) · CMC Development Advisor
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Over 35 years in biopharmaceutical CMC development and manufacturing. Previously Vice President of Manufacturing at Coulter Pharmaceutical (leading CMC for Bexxar™) and Vice President of Process Development at Corixa Corporation. Earlier roles at Genentech (Protropin™, Activase™) and Immunex (Leukine™, Enbrel™). Has supported CMC development from preclinical to post-registration stage for clients across North America, Europe, and Asia-Pacific. B.S. in Fermentation Science, University of California at Davis.

Masaru Kamishohara
Masaru Kamishohara, D.V.M., Ph.D.
Preclinical & Clinical Development Consultant; formerly Otsuka Pharmaceutical Medical Affairs Oncology · Clinical Development Advisor
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Decades of translational medicine and oncology drug development across pharmaceutical, biotech, and academic settings. Former Science Manager in Medical Affairs Oncology at Otsuka Pharmaceutical, contributing to clinical development of cancer therapeutics including the BCR-ABL tyrosine kinase inhibitor ponatinib (Iclusig®). Former President & CEO of Argenes, Inc. Has also served as Specially Appointed Associate Professor and Vice Director at Hokkaido University's Clinical Research and Development Center. D.V.M. and Ph.D., University of Tokyo (1995).

Gregory Liu
Gregory Liu
Senior Consultant, GlycoNex Inc. · Clinical Development Advisor
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Over 20 years of oncology drug development experience spanning clinical evaluation, strategic trial design (Phase I–III), and project management. Previous senior roles at PharmaEngine (VP, Translational Science) and AstraZeneca Taiwan (Manager, Clinical Research). M.S. in Pharmaceutical Sciences (Pharmacotherapeutics), St. John's University School of Pharmacy.

Mitsuo Nishikawa
Mitsuo Nishikawa, Ph.D.
Biotechnology Consultant; formerly Kirin Pharma / Kyowa Hakko Kirin · Preclinical Development Advisor
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Twenty years of antibody and hematopoietic stem cell research at Kirin Brewery's pharmaceutical division (now Kyowa Kirin) in Takasaki, Gunma, Japan, where he led patent programs for HSC expansion methods and the AMM2 anti-Mpl monoclonal antibody. Author of foundational work on thrombopoietin signaling and HSC bone marrow niche biology published in Blood, PNAS, and Stem Cells and Development. Collaborated internationally with the University of Michigan and the University of Tsukuba on in vivo HSC niche imaging.

Linda Pullan
Linda Pullan, Ph.D.
Founder, Pullan Consulting; Member of the Supervisory Board, NLC Health Ventures · Business Development Advisor
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Over 30 years of pharmaceutical and biotech business development experience, with a track record of more than 150 completed transactions ranging from preclinical candidate licensing to multinational acquisitions. Founder of Pullan Consulting (since 2006), advising biotech and pharmaceutical clients in the US, Europe, and Asia on partnering strategy, valuation, and negotiation. Previously Director of Licensing at Amgen (oncology & hematology), VP of Business Development at Kosan Biosciences, and led early in-licensing at AstraZeneca. Joined the Supervisory Board of NLC Health Ventures in June 2024. Frequent speaker at BIO-Europe and negotiation trainer at EBD Academy. Ph.D. in Biochemistry, UC Riverside; B.S. in Chemistry, University of Utah.

David Rabuka
David Rabuka, Ph.D.
Co-founder, CEO & President, Acrigen Biosciences · Preclinical Development Advisor
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Site-specific bioconjugation and ADC chemistry specialist. Co-founder of Acrigen Biosciences (Berkeley, CA), developing precision gene editing therapeutics. Previously co-founded Redwood Bioscience with Carolyn Bertozzi (2022 Nobel Laureate in Chemistry), where he developed the SMARTag® site-specific ADC conjugation platform — acquired by Catalent Pharma Solutions in 2014, where he subsequently served as Global Head of R&D, Chemical Biology. Author of over 45 peer-reviewed publications and inventor on more than 30 patents. Ph.D. in Chemistry, UC Berkeley (Bertozzi lab, Chevron Fellow).

Christopher Stewart
Christopher Stewart, Ph.D., DABT
Principal Consultant, SGI Consulting, LLC · Preclinical Development Advisor
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Over 30 years in nonclinical toxicology and preclinical drug development, with extensive regulatory experience across US FDA, US EPA, OECD, and Japan MHLW GLP frameworks. Diplomate of the American Board of Toxicology (DABT). Has authored or reviewed over 300 regulatory submissions following ICH guidelines. Previous research and management roles at MPI Research, Charles River Laboratories, Arkansas Children's Hospital, and the US FDA. Past President of the Society of Toxicology's Toxicologists of African Origin Special Interest Group.

Toshiyuki Suzawa
Toshiyuki Suzawa, Ph.D.
President & CEO, BioStrad Lab LLC; Head Director of CMC Development, Chiome Bioscience Inc. · CMC Development Advisor
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Twenty years of biopharmaceutical CMC and process development in monoclonal antibodies and recombinant proteins, from early-stage discovery to commercial life-cycle management. Previously General Manager of the Production & Development Center at Fujifilm Kyowa Kirin Biologics. Has participated in JPMA's Biopharmaceutical Technology Working Committee (2015–2019) and contributed as an ICH Q12 EWG expert. Visiting Professor at Gunma University. Ph.D., Tokyo Institute of Technology.

03 — Facility

End-to-end execution from one Taipei site

GlycoNex operates from a single facility in Xizhi, New Taipei City, integrating R&D, process development, and GMP manufacturing under one roof. The site houses GMP-compliant antibody production at two scales — a 50 L intermediate bioreactor and a 200 L production-scale system — capable of supporting Phase 1 clinical drug supply and external CDMO partners. The facility's vertical integration spans antibody discovery, cell line establishment, upstream and downstream process development, scale-up, and quality control, enabling end-to-end execution from target identification through clinical-grade material delivery.

04 — Sustainability

Governance and environmental commitments

GlycoNex maintains an ongoing commitment to environmental and social sustainability, including energy reduction, emissions intensity tracking, and corporate governance practices appropriate to its position as a Taiwan OTC-listed company. Specific year-over-year metrics, the latest sustainability report, and corporate governance evaluation results are available upon request.

05 — Community & Talent

Supporting Taiwanese biomedical research and training

GlycoNex has provided multi-year support for Taiwanese biomedical education and antibody research initiatives, with contributions to 醣質基金會 (Glycoscience Foundation), Taipei Medical University, the Taiwan Antibody Society, and the Asia-Pacific Society of Pharmacology.

Since 2016, GlycoNex has hosted eight student researchers through internship and coursework partnerships with Taiwanese universities, contributing to the development of the next generation of biotechnology talent.

Reach us

Corporate information

Address

GlycoNex, Inc. 台灣醣聯生技醫藥股份有限公司

8F, No. 97, Sec. 1, Xintai 5th Rd.
Xizhi District, New Taipei City 221
Taiwan

Contact

Phone +886-2-2697-4168
Email mail@glyconex.com.tw

Please indicate inquiry type in your subject line:

  • Partnering Inquiry — business development
  • CDMO Inquiry — manufacturing services
  • Investor Relations — investor matters
Listing & Investor Relations

Stock TWO:4168
Taipei Exchange OTC market

Listed 2012

Connect with GlycoNex

Whether you're exploring partnership opportunities, evaluating CDMO capacity, or following our clinical milestones, our team is reachable directly.